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Clinical Trials/NCT04652934
NCT04652934
Completed
N/A

Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury: Randomized, Controlled, Multi-Centric, Single-Blind Clinical Trial

Vanesa Abuín1 site in 1 country24 target enrollmentJanuary 26, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hemiplegia and Hemiparesis
Sponsor
Vanesa Abuín
Enrollment
24
Locations
1
Primary Endpoint
Changes in Upper Limb Pain to Pressure
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The main objective:

To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life.

Hypothesis:

Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.

Detailed Description

Randomized clinical trial with blinding of the subject, the evaluator and the person analyzing the data. In the experimental group will be performed neural mobilitazion technique, while in the sham a technique to mimic neurodynamic. The assessment will be made by a single evaluator.

Registry
clinicaltrials.gov
Start Date
January 26, 2022
End Date
July 28, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Vanesa Abuín
Responsible Party
Sponsor Investigator
Principal Investigator

Vanesa Abuín

PhD students Thesis Director

Universidad Europea de Madrid

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of acquired brain injury (hemiplegia-hemiparesis)
  • Ages between 25 and 50 years

Exclusion Criteria

  • Unable to understand and respond to verbal instructions
  • Absence of voluntary movement in the upper limb
  • Take medicine for spasticity
  • Botulinum toxin infiltration in the last 6 months

Outcomes

Primary Outcomes

Changes in Upper Limb Pain to Pressure

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

Algometer

Changes in Muscle Strength

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

Dynamometer

Changes in Manual Ability

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

Abilhand Scale; Score 0(worse outcome)-2(better outcome)

Changes in Muscle Spasticity

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

MAS (Modified Ashworth Scale) 0 (better outcome) - 4 (worse outcome)

Changes in Nervous Conduction

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

Delsys Trigno Avanti (surface eMG for non-invasive assessment of muscles)

Changes in Upper Limb Pain Perception

Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)

EVA (Visual Analog Scale) 0 (worse outcome) - 10 (better outcome)

Study Sites (1)

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