Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury

Not Applicable

Completed

• Conditions: Acquired Brain Injury; Hemiplegia and Hemiparesis

• Registration Number: NCT04652934
• Lead Sponsor: Vanesa Abuín

Brief Summary

The main objective:

To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life.

Hypothesis:

Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.

Detailed Description

Randomized clinical trial with blinding of the subject, the evaluator and the person analyzing the data.

In the experimental group will be performed neural mobilitazion technique, while in the sham a technique to mimic neurodynamic.

The assessment will be made by a single evaluator.

Study Timeline

• Study First Submitted: 2020-10-08
• Study First Submitted QC: 2020-11-26
• Study First Posted: 2020-12-03
• Study Start: 2022-01-26
• Status Verified: 2023-07
• Primary Completion: 2023-07-28
• Study Completion: 2023-07-28
• Last Update Submitted: 2023-07-28
• Last Update Posted: 2023-08-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Diagnosis of acquired brain injury (hemiplegia-hemiparesis)
• Ages between 25 and 50 years

Exclusion Criteria

• Unable to understand and respond to verbal instructions
• Absence of voluntary movement in the upper limb
• Take medicine for spasticity
• Botulinum toxin infiltration in the last 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Changes in Muscle Strength	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	Dynamometer
Changes in Upper Limb Pain to Pressure	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	Algometer
Changes in Manual Ability	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	Abilhand Scale; Score 0(worse outcome)-2(better outcome)
Changes in Muscle Spasticity	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	MAS (Modified Ashworth Scale) 0 (better outcome) - 4 (worse outcome)
Changes in Nervous Conduction	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	Delsys Trigno Avanti (surface eMG for non-invasive assessment of muscles)
Changes in Upper Limb Pain Perception	Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)	EVA (Visual Analog Scale) 0 (worse outcome) - 10 (better outcome)

Trial Locations

Locations (1)

Federico Salniccia; 🇪🇸 Madrid, Spain