Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury: Randomized, Controlled, Multi-Centric, Single-Blind Clinical Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 24
- Locations
- 2
- Primary Endpoint
- Changes in Upper Limb Pain to Pressure
Study Overview
Brief Summary
The main objective:
To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life.
Hypothesis:
Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.
Detailed Description
Randomized clinical trial with blinding of the subject, the evaluator and the person analyzing the data.
In the experimental group will be performed neural mobilitazion technique, while in the sham a technique to mimic neurodynamic.
The assessment will be made by a single evaluator.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 25 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Diagnosis of acquired brain injury (hemiplegia-hemiparesis)
- •Ages between 25 and 50 years
Exclusion Criteria
- •Unable to understand and respond to verbal instructions
- •Absence of voluntary movement in the upper limb
- •Take medicine for spasticity
- •Botulinum toxin infiltration in the last 6 months
Outcomes
Primary Outcomes
Changes in Upper Limb Pain to Pressure
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Algometer
Changes in Muscle Strength
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Dynamometer
Changes in Manual Ability
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Abilhand Scale; Score 0(worse outcome)-2(better outcome)
Changes in Muscle Spasticity
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
MAS (Modified Ashworth Scale) 0 (better outcome) - 4 (worse outcome)
Changes in Nervous Conduction
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Delsys Trigno Avanti (surface eMG for non-invasive assessment of muscles)
Changes in Upper Limb Pain Perception
Time Frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
EVA (Visual Analog Scale) 0 (worse outcome) - 10 (better outcome)
Secondary Outcomes
No secondary outcomes reported
Investigators
Vanesa Abuín
PhD students Thesis Director
Universidad Europea de Madrid