rinary markers for fetal growth restriction: the role of gaseous vasoactive molecules.
Completed
- Conditions
- Fetal growth restrictionfetal growth retardation10016849
- Registration Number
- NL-OMON43012
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 51
Inclusion Criteria
Fetal growth restriction
hypertension
Exclusion Criteria
o Congenital anomalies
o being unable to understand the study information either caused by language differences or low
IQ
o Ruptured membranes
o Diabetes Mellitus (defined as use of insulin)
o Auto-immune disease
o Renal disease
o Seropositive for HIV
o HELLP
o Multiple pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Urinary metabolites and metabolites in blood related to composite neonatal<br /><br>consisting of fetal weight, length, matched for gestational age. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Placental histology, Doppler abnormalities, mode of delivery, APGAR scores and<br /><br>admission to NICU/ward and the relation of the urinary metabolites to the<br /><br>measurements of these molecules in maternal and fetal blood (umbilical cord<br /><br>blood).</p><br>