ACTRN12610000389000Completed未知
The feasibility and preliminary clinical utility of 11C-Methionine and 18F-Fluorothymidine Positron Emission Tomography-Computerised Tomography (PET-CT) imaging following radiotherapy and 2-3 cycles of adjuvant chemotherapy in patients with high grade glioma in order to assess time to progression, overall survival and 6 month progression-free survival.
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 Years to o limit (—)
- Sex
- All
Inclusion Criteria
- •Histologically confirmed malignant glioma (grades III-IV), Received surgical biopsy or debulking, radiotherapy, and commenced adjuvant chemotherapy with a temozolomide-containing chemotherapy regimen, Planned for routine MRI following 2 or 3 cycles of adjuvant chemotherapy, Eastern Cooperative Oncology Group (ECOG) performance status 0-2, able to undertake MRI and PET-CT imaging, written informed consent.
Exclusion Criteria
- •Pregnancy, age less than 18 years, Medical contraindication to MRI or PET-CT imaging, Cognitive impairment considered to impair the ability to give written informed consent in the opinion of the treating clinician
Investigators
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