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Clinical Trials/NCT05965037
NCT05965037
Completed
N/A

Multicenter Prospective Registry in Current Clinical Practice With the Non-compliant Coronary Angioplasty Balloon Catheter. The FLUYDO NC Post Market Clinical Follow-up Study

Alvimedica1 site in 1 country100 target enrollmentNovember 1, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Coronary Artery Disease
Sponsor
Alvimedica
Enrollment
100
Locations
1
Primary Endpoint
Device success
Status
Completed
Last Updated
last year

Overview

Brief Summary

The aim of the present observational study is to collect clinical data on the medical device non-implantable medical device Fluydo NC: coronary angioplasty non-compliant balloon dilatation catheter in the daily use in a not selected population.

Registry
clinicaltrials.gov
Start Date
November 1, 2022
End Date
June 15, 2023
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Alvimedica
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Turkish citizen,
  • ≥18 years of age,
  • Has indication for percutaneous transluminal coronary angioplasty (PTCA),
  • Has indication to treat obstructive lesions of a native coronary artery or aortocoronary bypass or needs post dilatation of coronary stent
  • Fluydo NC using in the primary lesion treated during the procedure by the decision physician,
  • Has signed and dated the informed consent.

Exclusion Criteria

  • Has a previous diagnosis of coronary artery spasm in the absence of a significant stenosis.
  • Needs the device use in an unprotected left main coronary artery
  • Device use has not consistent with Instructions for Use.
  • Participating in another medical device or pharmaceutical clinical trial.

Outcomes

Primary Outcomes

Device success

Time Frame: immediately after interventional procedure

No life-threatening arrhythmias (sustained ventricular tachycardia, ventricular fibrillation)

Time Frame: immediately after interventional procedure

Successful inflation, achievement of appropriate diameter, and deflation of the balloon

Time Frame: immediately after interventional procedure

Decrease in the percent stenosis after balloon procedure

Time Frame: immediately after interventional procedure

No perforation, flow-limiting dissection or reduction in Thrombolysis in Myocardial Infarction (TIMI) flow grade

Time Frame: immediately after interventional procedure

Secondary Outcomes

  • Rate of Target Lesion Failure (TLF) Measurement: Percentage of a composite of cardiac death, target vessel myocardial infarction (TV-MI), and CI-TLR.(discharge or 48 hours after index procedure, whichever happens first)
  • Procedural success: Measurement: Percentage of device success without major adverse cardiovascular events (MACE) (composite of all death, myocardial infarction (MI), and clinically indicated target lesion revascularization (CI-TLR))(Discharge or 48 hours after index procedure, whichever happens first)

Study Sites (1)

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