Phase I study of TS-1 and Nedaplatin for previously untreated patients with advanced squamous cell carcionoma of lung
- Conditions
- Squamous cell carcinoma of lung
- Registration Number
- JPRN-UMIN000009760
- Lead Sponsor
- Pulmonary Medicine, NHO Kyoto Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 15
Not provided
1.Interstitial pneumonia or pulmonary fibrosis detectable on chest radiograph. 2.Massive pericardial, pleural effusion or ascites 3.SVC syndrome 4.Symptomatic brain metastasis 5.Active concomitant malignancy 6.Uncontrollable diabetes mellitus or hypertension 7.Liver cirrhosis 8.Myocardial infarction within 6 months, unstable angina, those who received PTCA or CAGB within 6 months, congestive heart failure, uncontrollable arrhythmia 9.Pregnant or lactating women or those who declined contraception. 10.Severe drug allergy 11.Acute inflammatory diseases 12.Refusal against blood transfusion or other supportive therapies 13.Evidence of bleeding diathesis 14.Active infection 15.Those judged to be not suitable by the attending physician 16.Planning of thoracic radiotherapy during the trial.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method