NCT02516475已完成2 期
Effects of Zinc Supplementation on Weight, Body Mass Index (BMI), Waist Circumference, Fat Mass and Lean Mass, Apelin and Inflammatory Markers in Obese Individuals
National Nutrition and Food Technology Institute0 个研究点目标入组 50 人开始时间: 2014年10月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 主要终点
- weight
研究概览
简要总结
To study the effects of zinc supplement on anthropometric factors, Apelin and inflammatory markers in obese individuals, 50 obes person who referred to Diet and Nutrition clinic of Shahid Beheshti University of Medical Sciences will be randomly allocated to receive 50 mg zinc capsules or placebos for 15 weeks; both groups will be advised to adherence the investigators' diet . At the first and the end of the intervention,weight, body mass index (BMI), waist circumference, fat mass and lean body mass, concentration of zinc, albumin, hs-CRP, TNF-α and plasma apelin will be assessed and compared between groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age of 18 to 45 years
- •Non-smoking
- •Body Mass Index (BMI) more than 30
排除标准
- •Pregnancy, lactation or menopause in women
- •History of liver disease, kidney, thyroid, diabetes and other metabolic diseases
- •Use of drugs interfering with lipid profile, blood-thinning drugs, beta-blockers
- •Patients with immune deficiency
- •Use of zinc, calcium and iron supplement in the last 2 months
- •Use of weight loss medication or special diet
- •Following program to lose weight in recent 2 months
- •Recent surgery
结局指标
主要结局
weight
时间窗: 15 weeks
次要结局
未报告次要终点
研究者
Dr Azita Hekmatdoost
Principal Investigator
National Nutrition and Food Technology Institute
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