Skip to main content
MedPathMedPath Home
Clinical Trials/ACTRN12613000372785
ACTRN12613000372785
Not Yet Recruiting
Phase 3

An investigation of the effects of Baclofen on the amount of high frequency beta activity during quantitative electroencephalography in alcohol dependent participants.

Royal Adelaide Hospital0 sites20 target enrollmentApril 8, 2013
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsAlcohol Use DisorderMental Health - Other mental health disorders

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Alcohol Use Disorder
Sponsor
Royal Adelaide Hospital
Enrollment
20
Status
Not Yet Recruiting
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 8, 2013
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Severe Alcohol Use Disorder
  • •Abstinent from alcohol for 1 week
  • •Willing and able to provide informed consent to participate in the study

Exclusion Criteria

  • •1\.Opiate, Stimulant, Inhalant or Benzodiazepine dependence
  • •2\.History of dementia or severe brain injury or Mini Mental score \< or \= 26/30
  • •3\.Receiving baclofen or diazepam medication in the 5 days prior to the study
  • •4\.Receiving any regular medication which may significantly change EEG activity including anticonvulsants, benzodiazepines or other sedatives. (This specifically does not include oral contraceptives, thiamine, multivitamins, thyroxine, naltrexone, nicotine replacement therapy or antidepressants.)
  • •5\.Acamprosate ( A medication for alcohol dependence which has a mechanism of action which could interact with the mechanism of action of Baclofen)
  • •6\. Renal function where creatinine clearance is less than 50ml/min.
  • •7\.Pregnancy or breast feeding
  • •8\.History of intolerance to baclofen
  • •9\.Contraindications/precautions ( as listed in the product information) to baclofen
  • •10\.Past history of major medical condition.

Outcomes

Primary Outcomes

Not specified

Similar Trials

Recruiting
Phase 3
To examine how well Baclofen and Naltrexone work as medications in individuals with alcohol addiction and withdrawal symptoms.Health Condition 1: F102- Alcohol dependence
CTRI/2024/06/069491Rahul
Not Yet Recruiting
Phase 4
A study to compare whether oral baclofen or oral tizanidine is better in patients presenting with tightness of the upper limb after stroke.Health Condition 1: G811- Spastic hemiplegia
CTRI/2024/03/064651Jalpaiguri Government Medical College and Hospital
Active, Not Recruiting
N/A
Efficacy evaluation of oral baclofen treatment versus intrathecal baclofen in children with dystonic cerebral palsy - Oral/intrathecal therapy in children with dystoniaDystonic or spastic dystonic cerebral palsyMedDRA version: 9.1Level: SOCClassification code 10029205MedDRA version: 9.1Level: PTClassification code 10008129MedDRA version: 9.1Level: LLTClassification code 10021740
EUCTR2008-000833-23-ITAZIENDA OSPEDALIERA ISTITUTI CLINICI DI PERFEZIONAMENTO DI MILANO
Completed
N/A
Effect of sustained release baclofen on alleviation of gastro-esophageal reflux disease symptoms
ACTRN12613000910707Shahid Beheshti University of Medical Sciences40
Active, Not Recruiting
N/A
A placebo controlled trial with Baclofen for the treatment of GERD patients with incomplete PPI responseGastroesophageal reflux disease
EUCTR2009-017351-96-BEZleuven