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临床试验/NCT06437990
NCT06437990已完成不适用

Pilot Study of Arteriovenous Loop Graft for Free Functional Gracilis Transfer in Brachial Plexus Injured Patients With Insufficient Flow of Donor Artery

Siriraj Hospital1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2015年11月19日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Viability of the flap

研究概览

简要总结

Free functional muscle transfer (FFMT) using the gracilis muscle as a donor muscle has become a standard treatment for reconstructing late-onset brachial plexus injuries. Successful implementation of this procedure relies on the availability of functional donor vessels in the injured limb to supply the muscle flap. However, some brachial plexus injuries are accompanied by subclavian or axillary artery injuries, which compromise the viability of the muscle flap due to insufficient vascular supply. To address this, arteriovenous (AV) loop grafts have been employed to extend donor vessels to the flap and have been utilized in various body regions, including the upper extremity. Despite their widespread use, AV loop grafts have not been previously utilized in FFMT for late-onset brachial plexus injuries with concurrent subclavian or axillary artery injuries. This study aimed to assess the feasibility of this surgical approach and report the long-term outcomes of the procedure.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age equal or more than 20 years old
  • •Patients with brachial plexus injury with depletion of blood flow to the injured limb which confirmed by abnormal computed tomography arteriogram

排除标准

  • •Patients who had sufficient thoraco-acromial or thoraco-dorsal artery blood flow for standard free functional muscle transfer operation without the need of an AV loop graft

研究组 & 干预措施

Arteriovenous loop graft

Experimental

A saphenous vein graft was used to create an arteriovenous loop from the common carotid artery to the external jugular vein, providing vascular supply for a free functional gracilis muscle flap in patients with late-onset brachial plexus injury.

干预措施: Arteriovenous loop graft (Procedure)

结局指标

主要结局

Viability of the flap

时间窗: 1 month

Survival of the flap after the surgery

次要结局

  • Motor power(12 months, 18 months)
  • Complications(1 month)
  • Operative time(1 month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Panai Laohaprasitiporn, MD

Assistant Professor

Siriraj Hospital

研究点 (1)

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