Does local application of betamethasonvalerate 0,1% cream twice a day reduce the complaints of chronic chillblains?
Completed
- Conditions
- Chronic pernionesChilblains
- Registration Number
- NL-OMON22759
- Lead Sponsor
- Radboud University Nijmegendepartment Womens Studies Medicine(head: Prof. Dr. A.L.M. Lagro Janssen).
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Population:
Patients with complaints of chronic chillblains referred to us in the winters of 2009-2010, 2010-2011 and 2011-2012 by GPs in the north west of the Netherlands. And subjects who attended our 2003-2004 study on the effect of vitamin D3.
Exclusion Criteria
1. A patient history of inflammatory disease;
2. Pregnancy;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We consider the intervention to be effective when a reduction of complaints or disability occurs of 10mm, as recorded by the subjects on a 100mm Visual analogue scale.
- Secondary Outcome Measures
Name Time Method Secundary we register side effects: skin irritation an signs of skin atrophy.