MedPath

Efficacy and Safety of Diclofenac Sodium Gel in Knee Osteoarthritis

Phase 3
Completed
Conditions
Osteoarthritis
Registration Number
NCT00171626
Lead Sponsor
Novartis
Brief Summary

This study will test the efficacy and safety of topical diclofenac sodium gel in the treatment of knee osteoarthritis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
480
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
WOMAC pain score in target knee at Week 12
WOMAC physical function score in target knee at Week 12
Global rating of disease activity by patient at Week 12
Secondary Outcome Measures
NameTimeMethod
WOMAC pain and physical function scores in target knee and global rating of disease activity by patient at Weeks 1, 4 and 8
WOMAC stiffness score, pain on movement and spontaneous pain in target knee, and global rating of benefit by patient, at Weeks 1, 4, 8 and 12
Pain on movement in target knee and use of rescue medication recorded in diary
Global evaluation of treatment at final visit
Treatment responder rate according to OARSI criteria

Trial Locations

Locations (1)

Novartis Consumer Health Inc

🇺🇸

Parsippany, New Jersey, United States

© Copyright 2025. All Rights Reserved by MedPath