Development and Validation of Models to Predict Postoperative Complications for Patients With Cardiac Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Surgery--Complications
- Sponsor
- China National Center for Cardiovascular Diseases
- Enrollment
- 70000
- Locations
- 1
- Primary Endpoint
- postoperative complications: ECMO
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
Patients undergoing cardiac surgery is routinely performed in clinical scenarios, highly postoperative morbidities and long-term mortality should be modified. A simple risk prediction model incorporating risk factors can help guide clinical decision making, patient counseling and treatment planning.
Detailed Description
Patients undergoing cardiac surgery is routinely performed in clinical scenarios, highly postoperative morbidities and long-term mortality should be modified.A nomogram is a pictorial representation of a scoring model that possesses a simple user interface and shows favorable predictive performance. By integrating a patient's diverse determinant variables, a nomogram can provide a personalized probability for quantitative predictions of the incidence of an outcome of interest.Therefore, we conducted a retrospective study to assess the incidence, risk factors and outcomes associated with major complications patients undergoing cardiac surgery.
Investigators
Yuefu Wang
Principal Investigator, Clinical Professor
China National Center for Cardiovascular Diseases
Eligibility Criteria
Inclusion Criteria
- •Age more than 18 years Undergoing Cardiovascular surgery
Exclusion Criteria
- •Missing primary outcomes or variables
Outcomes
Primary Outcomes
postoperative complications: ECMO
Time Frame: 30 days
patients with ECMO
postoperative complications: acute kidney injury
Time Frame: 30 dyas
Diagnosed acute kidney injury (KDIGO)
postoperative complications: Infection
Time Frame: 30 days
Diagnosed infection
postoperative complications: delirium
Time Frame: 30 days
Diagnosed delirium (CAM,CAM-ICU)
postoperative complications: MACCE
Time Frame: 30 days, as follow up
Diagnosed MACCE
postoperative complications: Chronic Kidney disease
Time Frame: 30 days, as follow up
Diagnosed Chronic Kidney disease
postoperative complications: major bleeding
Time Frame: 30 days
Diagnosed major bleeding
postoperative complications: postoperative pulmonary complications
Time Frame: 30 days
Diagnosed postoperative pulmonary complications
postoperative complications: IABP
Time Frame: 30 days
patients with IABP
Length of ICU stay
Time Frame: Through study completion, an average of 30 days
Number of days the patient stays in the intensive care unit
Ventilation time
Time Frame: Through study completion, an average of 7 days
Number of hours the patient with mechanical ventilation
Secondary Outcomes
- Total hospital costs(Through study completion, an average of 30 days)
- ICU costs(Through study completion, an average of 30 days)
- Length of hospital stay(Through study completion, an average of 30 days)
- Length of postoperative hospital stay(Through study completion, an average of 30 days)