Effects of RF Microneedle on Photoaging Skin
Not Applicable
Completed
- Conditions
- PigmentationPigmentation Disorder
- Interventions
- Device: RF MicroneedleDrug: Combination cream
- Registration Number
- NCT05710068
- Lead Sponsor
- Ajou University School of Medicine
- Brief Summary
Melasma relapse is almost common after discontinuation of conventional treatment. Recent studies have suggested that photoaging dermis is main pathomechanism of melasma emphasizing stromal targeting therapy. Therefore, we investigated maintenance effect of microneedle radiofrequency (RF) for melasma treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 15
Inclusion Criteria
- Adult more than 19 years old
- Melasma clinically diagnosed by three dermatologists
Exclusion Criteria
- Aesthetic medical procedures in three months prior to the study
- Use of topical depigmenting agents in three months prior to the study
- Pregnant or lactating
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Conventional therapy with RF microneedle RF Microneedle Half face Oral tranexamic acid combined with triple combination cream with RF microneedle Conventional therapy with RF microneedle Combination cream Half face Oral tranexamic acid combined with triple combination cream with RF microneedle Conventional therapy Combination cream Half face Oral tranexamic acid combined with triple combination cream
- Primary Outcome Measures
Name Time Method Change of lightness value Every 1 month up to 8 months Change of lightness value by a chromometer
Change of modified melasma area severity index score Every 1 month up to 8 months Change of modified melasma area severity index score
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ajou University Hospital
🇰🇷Suwon, Korea, Republic of