Effectiveness of a Post-deworming Education Intervention to Reduce Soil-transmitted Helminth Infections and Absenteeism in Grade 5 School-children in a Community of Extreme Poverty, Peruvian Amazon
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Enrollment
- 1,101
- Locations
- 1
- Primary Endpoint
- Soil-transmitted helminth re-infection (Ascaris, Trichuris, or Hookworm).
Overview
Brief Summary
To efficiently control soil-transmitted helminths (Ascaris, Trichuris, and hookworm), WHO, PAHO, and others recommend the inclusion of an education strategy in school-based deworming programs. However, the effectiveness of such a strategy on the rate of STH re-infection and on education indicators, such as absenteeism, remains to be fully understood. The proposed research aims to evaluate the effectiveness of a post-deworming education intervention targeted to Grade 5 school children enrolled in Belén's schools using a cluster-randomized trial design. Results will be used to inform school-based deworming programs in Peru and other similar endemic areas in Latin America and, indeed, around the world.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Girls and boys enrolled in Grade 5 in eligible schools located in the Belén district of Iquitos, Peru. Eligible schools have a minimum of 10 boys and 10 girls enrolled in grade
- •Informed written consent obtained from the parents or legal guardian of the child.
- •Verbal assent from child.
Exclusion Criteria
- •Parents (or guardians) refusing participation of their child.
- •Child who refuses to participate.
Outcomes
Primary Outcomes
Soil-transmitted helminth re-infection (Ascaris, Trichuris, or Hookworm).
Time Frame: 4 months post-deworming
Secondary Outcomes
- Absenteeism rate.(During the first 4 months following deworming)
- Eggs per grams reduction rate.(4 months post-deworming)
- Weight gain (kg)(4 months post-deworming)
- Height gain (cm)(4 months post-deworming)