DRKS00023738已完成4 期
Antibacterial and anti-plaque effect and substantivity of different toothpaste slurries - AB-AP_S_ZPsulurries
Klinik für Parodontologie und peri-implantäre Erkrankungen0 个研究点目标入组 24 人开始时间: 2021年3月4日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 70 Years（—）
- 性别
- All
入选标准
- •At the age between the age of 18-70 years; In good health; With least 20 own teeth (excluding wisdom teeth); Reassurement of an effective contraception; Non-smokers or former smokers for at least 1 year or occasional smokers with a maximum of 5 cigarettes per week; Willing not to use interdental cleaning devices that contain antibacterial agents, like amine fluoride, chlorhexidine, silver ions etc. during the full duration of the study.
排除标准
- •1. Severe systemic diseases (e.g. tumours, infectious diseases) and diseases that require regular systemic drugs (e.g., Anti-Hypertensives: Ca-Antagonists); 2. The use of systemic antibiotics during the last 3 months or local antimicrobials that may affect the plaque biofilm (antibacterial mouth rinses (e. g. chlorhexidine) 4 weeks or less prior recruitment); 3. Severe oropharyngeal infections, significant dental disorders, ongoing dental treatment or any other medical treatment of the oral cavity; 4. Any known allergy to previously used oral hygiene products and/or oral therapeutic agents and/or dental materials or a known allergy to any of the ingredients of the study products or standard toothpaste (e.g. Limonene), which are used during the study and the wash-out periods; 5. Participants with current periodontitis or non-physiological tooth mobility, any other pathological change of the oral mucosa or gingiva, poor oral hygiene (papilla bleeding index PBI >30%); 6. Chronic drug abuse (alcohol, etc.) or any other illness which does not allow the person to assess the nature and/or possible consequences of the study; 7. Smoking with more than 5 cigarettes per week,; 8. Participation in another clinical study within the previous 30 days or parallel to this study; 9. dual participation in this or another clinical study during the clinical phase; 10. Individuals unwilling to abstain from additional oral hygiene measures during the treatment phase; 11. Non-Caucasians and women being pregnant or breast feeding.
研究者
相似试验
已完成
不适用
Studying antibacterial and anti fungal properties by adding chitosan to complete denture tissue conditionersDenture stomatitis.Other forms of stomatitisK12.1IRCT20181130041801N1Tabriz University of Medical Sciences42
尚未招募
1 期
A study of antibacterial activities and mechanism of action of Ha-Rak against common pathogenic bacteria in Thailand.Antibiotic-resistant bacteria in Thailand.Acinetobacter baumannii,Pseudomonas aeruginosa,Enterococcus spp.,Escherichia coli,Staphylococcus aureus,Klebsiella pneumoniae,Ha-Rak,antimicrobial peptides,serum bactericidal activities,inflaTCTR20200731002Faculty of medicine siriraj hospital, Mahidol university30
尚未招募
3 期
Evaluation of Vedshakti-novel herbal mouth protect spray Among Dental students : A Randomized Clinical Trial.CTRI/2023/02/049960DR SNEHAL VILAS THAMKE
已完成
3 期
Antimicrobial effects of nanoparticles in complete prosthesesDenture Stomatitis.Other forms of stomatitisk12.1IRCT20150628022951N9Tabriz University of Medical Sciences42
招募中
2 期
Anticaries role of silver diamine fluoride and fluoride varnish in childreCTRI/2017/11/010543Self sponsored