Antibiotic prophylaxis versus placebo in uncontrolled diabetic patients undergoing teeth extraction: a double-blind,randomized trial

Research Laboratory LR 12SP10 Functional and Aesthetic Rehabilitation of Maxillary0 个研究点目标入组 180 人开始时间: 2021年1月4日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Male or female patients
•18 years or older
•Patients with known history of insulin-dependent diabetes or noninsulin-dependent diabetes mellitus with glycosylated hemoglobin levels between 8% and 11% the previous two to three months.
•Extraction requiring minimal instrumentations.

•Surgical extraction procedure
•Immuno compromised patients or patient having diseases or conditions associated with impaired wound or osseous healing like: HIV,AIDS,hematologicalneoplasia, following transplant surgery,patient undergoing chemotherapy,patient under or with antecedents of antiresorptive drugs administration (bisphosphonate, denosumab),patient undergoing or with history of radiation in the maxillafacial region,patient under immunosupressive drugs: corticosteroids, thalidomide
•Patients undergoing extractions of endodontically treated teeth
•Patient currently taking antibiotics at the time of extraction or have had
•antibiotics less than 3days prior to extraction
•Patient with habits wich are known to be determinal to oral wound
•healing such as smoking, alcohool…
•Co-existing of local or systemic infection
•Pregnant and lacting patients
•Recent use of any anti-inflammatory drugs (used within one month previous)
•Allergy to drugs used in the study
•Patients taking antibiotics within 1 week after extraction for other infectious diseases.
•Having a dental emergency
•Having acute dental or periodontal infections requiring antibiotic prescription

发起方

Research Laboratory LR 12SP10 Functional and Aesthetic Rehabilitation of Maxillary