Antibiotic prophylaxis protocol to prevent postoperative complications in uncontrolled diabetic patients undergoing simple teeth extractions: A randomized, double-blind, single-center trial

Phase 2

Not yet recruiting

• Conditions: Oral Health

• Registration Number: PACTR202101511724343
• Lead Sponsor: Research Laboratory LR 12SP10 Functional and Aesthetic Rehabilitation of Maxillary

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-04
• Last Update Posted: 2023-05-29

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Male or female patients
18 years or older
Patients with known history of insulin-dependent diabetes or noninsulin-dependent diabetes mellitus with glycosylated hemoglobin levels between 8% and 11% the previous two to three months.
Extraction requiring minimal instrumentations.

Exclusion Criteria

Surgical extraction procedure
Immuno compromised patients or patient having diseases or conditions associated with impaired wound or osseous healing like: HIV,AIDS,hematologicalneoplasia, following transplant surgery,patient undergoing chemotherapy,patient under or with antecedents of antiresorptive drugs administration (bisphosphonate, denosumab),patient undergoing or with history of radiation in the maxillafacial region,patient under immunosupressive drugs: corticosteroids, thalidomide
Patients undergoing extractions of endodontically treated teeth
Patient currently taking antibiotics at the time of extraction or have had
antibiotics less than 3days prior to extraction
Patient with habits wich are known to be determinal to oral wound
healing such as smoking, alcohool…
Co-existing of local or systemic infection
Pregnant and lacting patients
Recent use of any anti-inflammatory drugs (used within one month previous)
Allergy to drugs used in the study
Patients taking antibiotics within 1 week after extraction for other infectious diseases.
Having a dental emergency
Having acute dental or periodontal infections requiring antibiotic prescription

Study & Design

• Study Type: Interventional
• Study Design: Not specified