Developing and Piloting an Infection Prevention and Control Intervention to Reduce Hospital-acquired Infections in Cambodia and Lao PDR
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hospital-acquired Infections
- Sponsor
- National University of Singapore
- Enrollment
- 192
- Locations
- 1
- Primary Endpoint
- Changes in hand hygiene compliance among health workers from baseline to endline
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Hospital-acquired infections (HAIs) are significant public health issues, especially in low- and middle-income countries (LMICs). Hand hygiene and low-level disinfection of equipment (LLDE) practices among healthcare workers (HCWs) are essential to reduce HAIs. Various effective infection prevention and control (IPC) interventions to reduce HAI incidence have been developed. However, which interventions work effectively in LMICs has not been identified. The investigators aim to develop, pilot, and assess the feasibility and acceptability of an IPC intervention in Cambodia and the Lao People's Democratic Republic (PDR).
Detailed Description
This study consists of four phases guided by the Medical Research Council (MRC) framework. Three hospitals from each country will be selected. In Phase 1, the investigators will conduct a gap analysis of IPC implementation and practices among HCWs at each hospital through desk review, direct observation of hand hygiene and LLDE practices, in-depth interviews with HCWs, and key informant interviews with stakeholders. In Phase 2, the investigators will develop an IPC intervention based on results from Phase 1 and interventions selected from the literature review of IPC interventions in LMICs. In Phase 3, the investigators will pilot the developed intervention in the same hospitals selected in Phase 1. Finally, in Phase 4, the investigators will assess the feasibility and acceptability of the developed intervention among HCWs and stakeholders at the selected hospitals. The investigators will employ the MRC framework to develop and evaluate an intervention to reduce HAIs in both countries. The investigators will also use a theoretical framework to explore factors that are barriers and enablers for HCWs to improve hand hygiene compliance. With these approaches, the investigators will be able to develop a comprehensive intervention. Findings from this study would shed light on promising IPC interventions to reduce HAI incidence in Cambodia and Lao PDR. More importantly, the findings may be applied to other LMIC settings.
Investigators
Siyan Yi
Assistant Professor
National University of Singapore
Eligibility Criteria
Inclusion Criteria
- •Healthcare workers working in the selected wards and of chosen hospitals
- •Aged 18 years or above
- •Working in the selected wards of the chosen hospitals for at least six months
- •Being able and agreeing to provide informed consent to participate in the study
Exclusion Criteria
- •Interns and visiting healthcare workers
Outcomes
Primary Outcomes
Changes in hand hygiene compliance among health workers from baseline to endline
Time Frame: At endline (6 months after the intervention started)
The investigators will calculate hand hygiene compliance by having the hand hygiene action of alcohol hand rub or hand washing using soap and water divided by the hand hygiene opportunity and multiple with 100.
Secondary Outcomes
- Perceived feasibility and acceptability of the infection prevention and control intervention among HCWs and stakeholders(At endline (6 months after the intervention started))