ACTRN12617000793314已完成2 期
A Pilot, Randomised, Double-Blind Study of Vitamin C in the treatment of Vasoplegic Shock after Cardiac Surgery
Austin Hospital0 个研究点目标入组 50 人开始时间: 2017年5月30日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patients aged greater than or equal to 18 years
- •Admitted to the ICU for less than 6 hours following cardiac surgery
- •Vasoplegic syndrome in the postoperative period defined as:
- •a) need for continuous vasopressor infusion to maintain a mean arterial pressure greater than 65 mmHg AND
- •b) cardiac index equal to or greater than 2.2 L/min/m2 OR central venous O2 saturation less than 60%
排除标准
- •Use of vasopressors or inotropes in the preoperative period
- •Off-pump cardiac surgery
- •Chronic use of corticosteroid therapy
- •History of oxalate nephrolithiasis
- •Haemochromatosis
- •Glucose 6 phosphate dehydrogenase deficiency
- •Treating physician believes there is a cause for shock other than vasoplegic syndrome (eg: bleeding, fluid requirement, pneumothorax, pacemaker issues, or heart failure)
- •Treating clinician believes the study is not in the patient’s best interests
研究者
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