A Clinical Study to Compare the Efficacy of AsthiśṛṃkhalÄ Ghá¹›ta and AÅ›vagandhÄ CÅ«rṇa with AtibalÄmÅ«la KvÄtha in the patients of JÄnu SandhigatavÄta (Knee Osteo Arthritis)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To find out the effect of asthishrinkhala ghrit in compare to aswagandha churna with atibalamool kwatha by observing the changes in VAS for pain and WOMAC SCALE in the patient of janu sandhigatavata (Knee osteoarthritis)
研究概览
简要总结
Sandhigatavata occurs when vata lodges in sandhi. we can correlate janu sandhigatavat with knee osteoarthritis on the basis of clinical features. OA is defined as chronic joint disorder with detoriation of articular cartilage and bone at joint margin called osteophytes and capsular fibrosis. 30 patients who fullfill the inclusion criteria were selected through computer generated randomization method and allocated in two groups. one group was treated with asthishrinkhala ghrita and another group treated with aswagandha churna with atibalamool kwatha for 4 weeks and assessed the before and after treatment. However, the comparison between groups using unpaired t-tests indicated no significant difference in efficacy. Both asthishrinkhala ghrita and ashvagandha churna with atiabalamoola kwatha proved effective in Sandhigatavata patients, with no observable superiority of one over the other.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients fulfilling the ayurvedic as well as modern criteria of diagnosis of OA.
- •Patient with signs and symptoms of knee joint osteoarthritis.
- •Patients without any previous anatomical deformity.
排除标准
- •Female patients having pregnancy or lactating period.
- •Patient with associated disease which affects the outcomes or completion of the treatment i.e., cardiovascular disorders, osteoporosis, hyperthyroidism or hypothyroidism, obesity (BMI≥30), cancer, tuberculosis, rheumatoid arthritis, psoriatic arthritis, gout, kidney and liver disorders.
- •Patients having past traumatic history and complete loss of articular cartilage.
- •Patients who have history of previously joint transplantation.
结局指标
主要结局
To find out the effect of asthishrinkhala ghrit in compare to aswagandha churna with atibalamool kwatha by observing the changes in VAS for pain and WOMAC SCALE in the patient of janu sandhigatavata (Knee osteoarthritis)
时间窗: 2 weeks and 4 weeks
次要结局
- 1)To find out the changes of signs and symptoms in both groups of the patients of janu sandhigatavata.(2)To find out the changes in X-ray after taking of asthishrinkhala ghrita and aswagandha curna with atibalamool kwatha in the patients of janu sandhigatavata (Knee osteoarthritis))
研究者
Patel Gopiben Ghanashyambhai
J S Ayurveda Mahavidhyalaya and P D Patel Ayurveda Hospital