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Investigating some of the oral manifestations associated with neutropenia - a clinical cross-sectional study

Not Applicable
Completed
Conditions
Oral Health
Oral manifestations associated with neutropenia in patients with hematological malignancies undergoing chemotherapy
Registration Number
ISRCTN17585958
Lead Sponsor
Damascus University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
50
Inclusion Criteria

First group (patients with chemotherapy-induced neutropenia):
1. Patients diagnosed with hematological malignancy
2. Patients who received at least one cycle of chemotherapy
3. Patients developing neutropenia after chemotherapy, with an absolute neutrophil count (ANC) less than 1.5 x 10^9/L

Second group (patients without chemotherapy-induced neutropenia):
1. Patients diagnosed with hematological malignancy
2. The patient has received at least one cycle of chemotherapy
3. The patient does not present with post-chemotherapy neutropenia, and has an ANC greater than 1.5 x 10^9/

Exclusion Criteria

1. Patients receive radiation therapy as part of their treatment
2. The patient has been diagnosed with oral cancer
3. The patient is diagnosed with a non-hematological malignancy
4. The patient is diagnosed with diabetes

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Oral manifestations measured using clinical and visual diagnosis at a single timepoint<br>2. Periodontal diseases measured using clinical and visual diagnosis at a single timepoint<br>3. Quality of life measured using a questionnaire that concentrates on different aspects of life as a result of neutropenia/chemotherapy at a single timepoint<br>
Secondary Outcome Measures
NameTimeMethod
There are no secondary outcome measures
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