NCT02726815UnknownNot Applicable
Pain and Symptoms in Children With Advanced Cancer: a Longitudinal Study to Develop a Comprehensive Symptom Inventory
Royal Marsden NHS Foundation Trust1 site in 1 country40 target enrollmentStarted: March 2016Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Prevalence of all symptoms identified by child using the age appropriate Memorial Symptom Assessment Scale.
Study Overview
Brief Summary
Primary Objective
The aim of this research study is to develop a comprehensive inventory of symptoms that occur in children with advanced cancer who are receiving a specialist palliative care service.
Secondary Objectives
- To assess correlation between parent, child and nurse scores on the Memorial Symptom Assessment Scale (MSAS).
- To identify symptom prevalence in children with advanced cancer as identified by the child/young person (CYP), nurse and parent (to be analysed separately for parent, child and nurse).
- To identify whether there are any symptoms missing from the age appropriate MSAS as identified by the CYP, nurse and parent (to be analysed separately for parent, child and nurse).
- To identify whether any items on the age appropriate MSAS are not relevant to the population being studied (to be analysed separately for parent, child and nurse).
- To identify which symptoms cause the most distress as identified by the CYP, nurse and parent (to be analysed separately for parent, child and nurse).
- To identify degree of severity of each symptom as identified by the CYP, nurse and parent (to be analysed separately for parent, child and nurse).
- To identify which symptoms occur most frequently as identified by the CYP, nurse and parent (to be analysed separately for parent, child and nurse).
- To assess the trends between phase of illness and symptom profile, severity and distress.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 7 Years to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Any child/young person (CYP) aged 7 to 17 years and 364 days referred and accepted to the palliative care service (PATCH team) at the Royal Marsden (RM) will be eligible for inclusion. The PATCH team is responsible for co-ordinating palliative care services for children with both malignant and non-malignant conditions in the South Thames and South East Coast areas. The team can provide home visits, local hospital and hospice visits for symptom and palliative care advice. The team are also available by telephone 24 hours a day, 365 days a year to provide symptom advice to families and health care professionals from all settings who are caring for children known to the team. Acceptance to this service is via multidisciplinary team (MDT) discussion.
Exclusion Criteria
- •Severe cognitive impairment in the parent/carer
- •Lack of fluent English
- •Lack of ability to read and write English
- •Psychological concerns about the CYP and/or parent/carer. All potential participants will be discussed with the psychosocial team before being invited to participate.
Outcomes
Primary Outcomes
Prevalence of all symptoms identified by child using the age appropriate Memorial Symptom Assessment Scale.
Time Frame: 18 months
Prevalence of all symptoms identified by the parent using the same assessment tool as the child
Time Frame: 18 months
Prevalence of all symptoms identified by the nurse
Time Frame: 18 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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