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Anti-Mullerian Hormone (AMH) and Antral Follicle Count as Markers of Ovarian Reserve- Prospective Followup of Young Cancer Patients

Conditions
Infertility
Interventions
Biological: blood tests
Registration Number
NCT00930501
Lead Sponsor
Hadassah Medical Organization
Brief Summary

young female cancer patients have improving chances of survival. the main risk is a chronic damage to their ovarian reserve. This may lead to future infertility.

Detailed Description

our objective is to prospectively follow patients before and after their cancer treatment. this should help us learn of the gonadotoxicity of various treatments as well as be able to better consult these and future patients of the need of fertility preservation techniques.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
100
Inclusion Criteria
  • all females prior and after chemotherapy
Exclusion Criteria
  • do not consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Cancer patientsblood testswomen 5-45 yr olf pre and post chemotherapy
Primary Outcome Measures
NameTimeMethod
Anti mullerian hormone2 years
Secondary Outcome Measures
NameTimeMethod
antral follicle count2 years
FSH2 years
E2 and prog2 years
inhibin b2 years
menstrual history2 years

Trial Locations

Locations (1)

Hadassah

🇮🇱

Jerusalem, Israel

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