A prospective observational study of temporal change in pulmonary function during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in patients with non-small cell lung carcinoma.
Not Applicable
- Conditions
- non-small cell lung carcinoma
- Registration Number
- JPRN-UMIN000015569
- Lead Sponsor
- Division of Respiratory Medicine and Clinical Allergy,Fujita Health University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Not provided
Exclusion Criteria
1) History of thoracic radiotherapy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of change in DLCO from baseline after EGFR-TKI administration
- Secondary Outcome Measures
Name Time Method (1) Other spirometric parameters change (FEV1, FVC, and VC) from baseline (2) Change on thin-slice CT findings after EGFR-TKI treatment (3) Frequency and extent of adverse effect of EGFR-TKI (4) Response rate of EGFR-TKI