跳至主要内容
临床试验/CTRI/2026/01/101694
CTRI/2026/01/101694尚未招募不适用

Effect of Ayurvedic Management in Decompensated Liver Cirrhosis an observational single group retrospective study.

J.S. Ayurveda Mahavidyalaya and P.D. Patel Ayurvedic Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2026年2月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1

研究概览

简要总结

Decompensated Liver Cirrhosis (DLC) is the advanced and irreversible stage of chronic liver disease where the liver loses its functional capacity and presents with complications like ascites, jaundice, hepatic encephalopathy, variceal bleeding, coagulopathy and fluid retention. Liver transplantation is the only definitive treatment in modern medicine, but due to high cost, limited donor availability and strict eligibility criteria, most patients rely on supportive or palliative care. In Ayurveda, liver disorders are described under Yakrit Vikara, Kamala, Kumbha Kamala and Jalodara, caused mainly by aggravated Pitta and Rakta leading to progressive liver dysfunction. Ayurvedic management focuses on Shodhana (mainly Virechana), Samana, Rasayana, Tikshna dravyas, Kshara karma and dietary regulation including Takra, Dugdha, Yavagu, light and pitta-shamaka ahara along with fluid-salt restriction. This retrospective observational single-group study aims to evaluate the effect of Ayurvedic management in patients of Decompensated Liver Cirrhosis treated at P.D. Patel Ayurvedic Hospital. Hospital records from 2021–2025 will be analysed for age, diagnosis, symptoms, treatment details, laboratory parameters and Child-Pugh score. Improvement in symptoms like ascites, oedema, jaundice, appetite, urine output, abdominal girth and biochemical markers including bilirubin, albumin, SGPT, SGOT and INR will be assessed before and after treatment. Since there is a lack of systematically documented evidence regarding Ayurvedic management in advanced liver disorders, this study aims to provide clinical data and real-world outcomes to support future research and evidence-based practice. It bridges classical Ayurvedic principles with modern clinical evaluation to assess the efficacy of Shamana–Shodhana therapy in improving survival chances, quality of life and functional health status in Decompensated Liver Cirrhosis.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients clinically or radiologically diagnosed with decompensated liver cirrhosis and complication with ascites.
  • Laboratory findings with Hyperbilirubinemia.
  • Received exclusive Ayurveda Management for at least 1 month on IPD bases and 5 months OPD base follow up.
  • Complete Medical Records including LFTs and symptoms evaluation available.

排除标准

  • Pregnant women Hepatic cirrhosis due to cardiac causes, inherited metabolic causes.
  • Other major co – morbities like insulin dependent diabetes mellitus, bleeding piles, heart disease, renal failure.
  • Life threatening complications like encephalopathy and excessive gastrointestinal bleeding.
  • Incomplete documentation.

研究者

发起方
J.S. Ayurveda Mahavidyalaya and P.D. Patel Ayurvedic Hospital
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Ruchi Makwana

J.S Ayurved Mahavidhyalaya and P. D. Patel Ayurvedic Hospital

研究点 (1)

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