CTRI/2019/09/021311
Completed
未知
Evaluation of genotyping and therapeutic drug monitoring vs. only therapeutic drug monitoring as a strategy for risk minimization in epileptic patients on carbamazepine therapy: a randomized controlled trial
Dr Nithya Gogtay0 sites50 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes
- Sponsor
- Dr Nithya Gogtay
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •i) Patients diagnosed with epilepsy. ii) Patients on CBZ therapy for at least 3 months iii) Patients complaining of any ADRs to CBZ like giddiness, dizziness, etc. or no ADRs like giddiness, dizziness, etc.
Exclusion Criteria
- •i) Patients with epilepsy on CBZ therapy and are not willing to participate in the study.
- •ii) Genotype (CYP3A5 polymorphism) results known to participant from prior testing or available in medical record iii) Patients with neurological deficits (physical deficits e.g. paraparesis or paraplegia)
- •iv) Patients with history of drug /alcohol abuse
- •v) Evidence of gastrointestinal tract, renal, endocrine, cardiovascular diseases, etc.
Outcomes
Primary Outcomes
Not specified
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