CTRI/2019/09/021311已完成未知
Evaluation of genotyping and therapeutic drug monitoring vs. only therapeutic drug monitoring as a strategy for risk minimization in epileptic patients on carbamazepine therapy: a randomized controlled trial
Dr Nithya Gogtay0 个研究点目标入组 50 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •i) Patients diagnosed with epilepsy. ii) Patients on CBZ therapy for at least 3 months iii) Patients complaining of any ADRs to CBZ like giddiness, dizziness, etc. or no ADRs like giddiness, dizziness, etc.
排除标准
- •i) Patients with epilepsy on CBZ therapy and are not willing to participate in the study.
- •ii) Genotype (CYP3A5 polymorphism) results known to participant from prior testing or available in medical record iii) Patients with neurological deficits (physical deficits e.g. paraparesis or paraplegia)
- •iv) Patients with history of drug /alcohol abuse
- •v) Evidence of gastrointestinal tract, renal, endocrine, cardiovascular diseases, etc.
研究者
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