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Clinical Trials/IRCT201310083210N4
IRCT201310083210N4Completed未知

Evaluation of sertraline effects on the time of engraftmen and ?serum levels of such inflammatory and anti-inflammatory factors ?as IL-6, CRP and IL-10 in depressed HSCT patients?

School of pharmacy,Research of deputy ,Shahid Beheshti University Of Medical Sciences0 sites40 target enrollmentStarted: TBDLast updated:
Conditions

Trial Snapshot

Phase
未知
Status
Completed
Sponsor
Enrollment
40

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
18 years to 60 years (—)
Sex
All

Inclusion Criteria

  • Age between 18 to 60 ?years for allo-HSCT and auto-HSCT; presence of depression ?or based on Hospital Anxiety & Depression Scale (HADS) ; ?Stable & normal renal and liver function and ; Ability for oral ?taking of medication . Exclusion criteria: Patients with ?baseline kidney dysfunction (GFR less than 60 mL/min) ;Patients with ?abnormal LFT (bilirubin & ?aminotransferases level of more than 2 normal) ; Patient with sepsis or uncontrolled ?infection at baseline ; Patients unable to take orally ; Non-?cooporable patients with mental dysfunctionality ; pregnant or ?lactating women ; HIV+ patients ; Patients who who have taken ?antidepressant medication later than a month ago ;Intolerance of Sertraline adverse ?effects. ?

Exclusion Criteria

  • Not provided

Investigators

Sponsor
School of pharmacy,Research of deputy ,Shahid Beheshti University Of Medical Sciences

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