Tear Proteins and Diabetic Retinopathy
试验速览
- 阶段
- 不适用
- 入组人数
- 350
- 试验地点
- 1
研究概览
简要总结
Diabetes mellitus is becoming a global epidemic. There is a need to devise a non invasive method for detection of diabetes and its related complication. Tear proteins are easy to collect causing no harm to a patient and different studies indicate that tear proteins of diabetic patients are significantly different from non diabetic population. This difference in the composition of tear proteins become more pronounced with advancement of diabetic retinopathy.
详细描述
Diabetes mellitus causes a significant alteration in tear proteins. If we analyze tear proteins by means of electrophoresis, HPLC, and mass spectroscopy.
We can find different type of tear proteins in different grades of diabetic retinopathy these biomarkers can help in mass screening , diagnosis and management of diabetic population.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •diabetic patients with type 2 diabetes
- •age above 30
- •willing to participate
排除标准
- •ocular surface disorders.
- •collagen vascular diseases
- •Limbal hyperemia
- •previous ocular surgery
- •creatinine level above 1.0
- •liver diseases