Effect of oral Magnesium oxide on preoperative analgesia in hysterectomy

Phase 1

• Conditions: Pain after hysterectomy surgery.; Other acute postprocedural pain; G89.18

• Registration Number: IRCT20190819044559N1
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

No history of sensitivity to magnesium and naproxen
Lack of liver diseases
No kidney or cardiovascular dysfunction
no lactation
age between 35 to 65

Exclusion Criteria

drug or opiod addiction
neurological disorder, pain or abuse of opiod analgesic
Concomitant treatment with analgesics or anti-inflammatory drugs
Chronic treatment with magnesium or calcium channel blockers
Patients with complicated appendectomy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score after hysterectomy surgery. Timepoint: After surgery and consciousness of the patient. Method of measurement: VAS scale.;Pulse rate changes. Timepoint: During operation. Method of measurement: Arm cuff.;Blood pressure changes. Timepoint: During operation. Method of measurement: Arm cuff.;Time between end of operation and first prescription of analgesics. Timepoint: The first time that patient need analgesic. Method of measurement: patient demand.

Secondary Outcome Measures

Name	Time	Method
Chill feeling. Timepoint: After operation. Method of measurement: Clinical symptoms.;Nausea. Timepoint: After operation. Method of measurement: Clinical symptoms.;Vomiting. Timepoint: After operation. Method of measurement: Clinical symptoms.