Evaluating Tele-Emergency Care in Costs and Outcomes for Rural Sepsis Patients
- Conditions
- Sepsis
- Interventions
- Other: Telemedicine
- Registration Number
- NCT05072145
- Lead Sponsor
- Nicholas M Mohr
- Brief Summary
Sepsis is a life-threatening emergency for which provider-to-provider telemedicine has been used to improve quality of care. The objective of this study is to measure the impact of rural tele-emergency consultation on long-term health care costs and outcomes through decreasing organ failure, hospital length-of-stay, and readmissions.
- Detailed Description
Sepsis is responsible for over 1.7 million hospitalizations at a cost of $26 billion annually, making it the most expensive acute care condition in US hospitals. High-quality early sepsis care has been associated with decreased organ failure, shorter ICU and hospital length-of-stay, and improved survival. Rural sepsis patients are more likely to be transferred to tertiary centers, and they also have higher mortality and health care costs. ED-based telemedicine (tele-ED) consultation between a rural provider and a board-certified emergency physician may deliver the expertise to reduce care delays and improve outcomes while avoiding unnecessary costs.
In 2017, the study team partnered with Avera eCARE, the largest tele-ED provider in North America, to implement a standard telemedicine-based sepsis care pathway. Subsequently, the investigators showed (using patient-level primary data collection across several networks) that tele-ED use was associated with improved adherence with international sepsis guidelines.
In addition to its association with short-term clinical outcomes, however, the study team hypothesize that telemedicine may also decrease costs. The investigators have shown that high-quality sepsis care is associated with decreased readmissions and post-discharge mortality. High quality care may also prevent organ failure, avoid ICU admissions, reduce mechanical ventilation and vasopressor use, decrease ICU and hospital length-of-stay, and decrease post-discharge care-primarily through reducing avoidable organ failure. All of these factors are likely to have a significant effect in terms of reducing healthcare cost.
The objective of the proposed project is to measure the effect of tele-ED consultation at reducing healthcare costs and long-term outcomes in sepsis patients in rural EDs. The following primary hypotheses will be tested:
* Total healthcare expenses and 90-day mortality will be lower in patients treated in a tele-ED hospital, with the effect primarily through reduced hospital length-of-stay and fewer readmissions.
* Total expenses and mortality will be lower in cases where tele-ED is used vs. matched controls in non-tele-ED hospitals.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55772
- Sepsis, according to ICD-10 codes
- No infection diagnosed in the ED
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Tele-ED used Telemedicine Patient care was provided through tele-ED services
- Primary Outcome Measures
Name Time Method Total healthcare expenditures From hospital admission until 30 days after discharge Defined as direct inpatient and outpatient payments to hospitals and physicians, skilled nursing care, home care, durable medical equipment, and ambulance costs from the ED visit until 30 days post-discharge. Drugs are not included.
- Secondary Outcome Measures
Name Time Method Number of participants who die within 90 days of hospital admission From hospital admission until 90 days after admission 90-day mortality
Hospital length-of-stay From date of hospitalization through hospital discharge, assessed up to 90 days Duration of hospitalization
Inpatient care costs From the date of hospital admission through hospital discharge or 90 days, whichever comes first, all inpatient health care expenditures Total healthcare expenditures related to inpatient care in current hospitalizations
Inter-hospital transfer costs From the date of hospital admission through hospital discharge or 90 days, whichever comes first, all inter-hospital transfer health care expenditures Emergency medical services transfer costs and second emergency department costs (if transferred)
Post-discharge costs From the date of hospital discharge through 30 days after discharge, total health care expenditures health care expenditures Total healthcare expenditures
Emergency department costs From the date of hospital admission through hospital discharge or 90 days, whichever comes first, all emergency department health care expenditures Total healthcare expenditures related to emergency department care in current hospitalization
Number of participants requiring ICU care From the date of hospital admission through hospital discharge or 90 days, whichever comes first, the number of participants who are treated in an intensive care unit Any admission to the ICU
Readmission costs Between hospital discharge and 30 days after hospital discharge, related to inpatient re-hospitalization Total healthcare expenditures during readmission(s) within 30 days after initial hospital discharge
Trial Locations
- Locations (1)
University of Iowa Hospitals and Clinics
🇺🇸Iowa City, Iowa, United States