Show Me How You Move and I Will Tell You Who You Are

Completed

• Conditions: Vestibular Disease; Vestibular Function Disorder

• Registration Number: NCT06739577
• Lead Sponsor: Université Catholique de Louvain

Brief Summary

The aim of this experiment is to gain a better understanding of the body movement patterns of patients with balance disorders (following damage to the vestibular system), as well as their cognitive performance profile. To achieve this, we will need to assess the performance of both patients and healthy subjects with no balance disorders. We will be using a newly-developed artificial intelligence tool to analyze body movement patterns on the basis of participants' videos, and we will also be evaluating participants' performance in a few simple tests of reaction times to image presentations on computer and/or tablet/smartphone.

If you agree to take part in this experiment, you will be asked to perform a simple walking exercise in a corridor (filmed and supervised by a physiotherapist) as well as a few objective cognitive measurement tests (reaction time to attentional and vigilance tasks on computer and/or tablet/smartphone) and subjective tests (self-reported questionnaires) requiring around 40 minutes of investigation in total.

In the long term, the results of this research will make it easier to assess balance disorders in patients with vestibular pathology, and better quantify any cognitive difficulties they may have.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-10
• Primary Completion: 2023-07-01
• Study Completion: 2023-07-01
• Status Verified: 2024-12
• Study First Submitted: 2024-12-10
• Study First Submitted QC: 2024-12-17
• Last Update Submitted: 2024-12-17
• Study First Posted: 2024-12-18
• Last Update Posted: 2024-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age between 18 and 90 years old.
• Vestibular loss diagnosed by senior ENT doctors with the gold standard ENT measures (caloric testing, head impulse test and/or vestibular evoked myogenic potential, ocular and cervical).

Exclusion Criteria

• Previous neurological disorders (stroke, dementia, ...)
• Current medication interfering with the testing (reducing reaction time).
• Visual difficulties interfering with the testing (Visual field reduction,...)
• Age below 18 years old.

For healthy controls :

Inclusion criteria :

• Age between 18 and 90 years old.

Exclusion criteria:

• Previous neurological disorders (stroke, dementia, ...)
• Current medication interfering with the testing (reducing reaction time)
• Visual difficulties interfering with the testing (Visual field reduction,...)
• Vertigo or balance complains or an history of previous vestibular disorder.
• Age below 18 years old.
• Not being able to understand the consigns of the task.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Neuropsychological measures	Through the entire study, approximately 24 months	evaluation to assess subjective perception of cognitive difficulties associated to vertigo with the Neuropsychological Vertigo Inventory - NVI (Lacroix et al., 2016), using 28-items, each scored on a 5-point Likert scale and divided into 7 distinct subscales measuring attention, memory, emotion, space perception, time perception, vision, and motor abilities.; Higher scores = higher complains
Walking activity	Through the entire study, approximately 24 months	Participants performed the Timed-Up \& Go (TUG) four times (practice trial, normal, slow and fast speed). They have to stand up from a chair, walk until a line on the ground marked at 3 meters, turn, go back to the chair, and sit down again. The time is recorded. There is no time limit to the task.

Trial Locations

Locations (1)

Cliniques universitaires Saint-Luc; 🇧🇪 Brussels, Belgium