Long-Standing Persistant Atrial Fibrillation-Pulmonary Vein Isolation With or Without Ablation

Not Applicable

Completed

• Conditions: Tachycardia; Atrial Fibrillation
• Interventions: Procedure: pulmonary vein isolation with additional ablation of fragmented potentials; Procedure: pulmonary vein isolation

• Registration Number: NCT00820625
• Lead Sponsor: Asklepios proresearch

Brief Summary

The chronic success rate, defined as freedom from any atrial tachyarrhythmias will increase from 35% to 60% by ablation of complex fragmented atrial electrograms potentials in addition to pulmonary vein isolation (PVI) as compared to PVI alone in patients with long-standing persistent AF.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2009-01-09
• Study First Submitted QC: 2009-01-09
• Study First Posted: 2009-01-12
• Status Verified: 2017-02
• Primary Completion: 2017-02
• Study Completion: 2017-02
• Last Update Submitted: 2017-02-06
• Last Update Posted: 2017-02-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 124

Inclusion Criteria

• long standing persistent atrial fibrillation > 6 months and < 5 years

Exclusion Criteria

• renal failure
• left atrial size >55 mm

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	pulmonary vein isolation with additional ablation of fragmented potentials	ablation: pulmonary vein isolation with additional ablation of fragmented potentials
1	pulmonary vein isolation	ablation: pulmonary vein isolation

Primary Outcome Measures

Name	Time	Method
data collection in view of acute and chronic success rate	12 months

Secondary Outcome Measures

Name	Time	Method
data collection of complications in both groups and also procedure parameters	12 months

Trial Locations

Locations (1)

Asklepios Klinik St. Georg; 🇩🇪 Hamburg, Germany