Hypertension and exercise: an intervention study in older patients

Not Applicable

• Conditions: Hypertension; C14.907.489

• Registration Number: RBR-4ntszb
• Lead Sponsor: niversidade Federal do Rio Grande do Norte – UFR

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Both sexes; aged 60-80 years; previous diagnosis of hypertension; self-reported and clinically assessed physical activity readiness; unchanged pharmacological plan for hypertension in the last 4 weeks; willing to engage in any of the interventions; not engaging in a regular physical activity program in the past 3 months; insufficiently active (i.e., not performing 150 min/week of moderate physical activity and/or 75 min/week of vigorous physical activity, assessed through 7-day accelerometry)

Exclusion Criteria

Being unable or refusing to sign the consent form; previous cardiovascular events or diseases (e.g. unstable angina, severe arrhythmia, acute myocardial infarction, coronary artery disease, stroke, deep vein thrombosis, peripheral artery disease, uncontrolled arrhythmia, pacemaker use, etc.); limiting chronic pulmonary disease (emphysema, chronic bronchitis, asthma); chronic kidney disease in need of dialysis; incidence of cardiovascular or pulmonary events during the study; uncontrolled hypertension (> 160/105 mmHg); diabetes with insulin use or decompensated (fasting glucose > 300 mg/dl); high alcohol intake (>14 doses per week); self-reported or perceived language, hearing or sight limitations that may come to hinder participation; exercise contraindication, as indicated on the maximum cardiopulmonary exercise test (e.g. EKG alterations suggesting myocardial ischemia); osteomioarticular issues that may prevent performing maximal cardiopulmonary exercise testing and moderate-to-vigorous aerobic exercise or osteomioarticular injury during the study (e.g. muscle injury resulting in limitations for exercise); neurological progressive disorders (Parkinson, multiple sclerosis, Alzheimer); cancer demanding treatment in the past two years

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in ambulatory systolic blood pressure levels after 12 weeks of aerobic training, assessed through ambulatory blood pressure monitoring, through the confirmation of a decrease of at least 4 mmHg between pre- and post-intervention measurements compared to the control group