Association of contrast spread pattern and clinical outcomes in cervical epidural injectio

Not Applicable

Completed

• Conditions: Diseases of the musculoskeletal system and connective tissue

• Registration Number: KCT0006398
• Lead Sponsor: The Catholic University of Korea, Seoul St. Mary's Hospital

Brief Summary

Overall, 60% of the participants experienced more than 50% pain reduction in NRS pain scores. Statistically significant difference was discovered in patients with longer duration of the symptoms, cervical pathology higher than C4-5 level, and moderate to severe central stenosis. Variable findings were assessed on the clinical result of CILESI by different contrast spread patterns. Only the contrast spread pattern of grade 3 resulted to have notable success rate whereas the contribution to success could not be made from the grade 1 and 2. The grade 4 rather resulted significantly unsuccessful result. Univariate analysis demonstrated that factors associated with unsuccessful outcomes were the longer duration of the symptoms, higher pathological lesion above the C4-5 level, moderate to severe central stenosis, and the contrast spread pattern of grade 4 (Table 2). On further multivariable analysis, the duration of the symptoms, high grade of central stenosis, and the grade 4 dye dispersion on epidurography were to be linked to unsuccessful prognosis. Primary poor prognostic factor was analyzed to be the CILESI with the contrast only sread to the dorsal epidural place and no further. Grade 4 spread pattern yielded nearly 9 times worse outcomes that grade 1.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-01-31
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

CT MRI herniated nucleus pulposus spinal stenosis
3)Numeric rating scale (NRS) 5

Exclusion Criteria

Patients with any history of surgery on cervical spine
Patients with any history of cervical neuroplasty of cervical nucleoplasty
Patients with any trauma history of car accident
Patients with neoplastic disease
Patients complaining pain on both sides of the upper extremity
Patients who were not present on one-month follow-up visits

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Degree of pain relief

Secondary Outcome Measures

Name	Time	Method
Contrast spread pattern on fluoroscopic epiduroscopy