Evaluation of Interleukin 18 in Chronic periodontitis
- Conditions
- Chronic periodontitis.Chronic periodontitis
- Registration Number
- IRCT201404133795N2
- Lead Sponsor
- Ahvaz Jundishapour University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusin criteria: patients with severe periodontitis; patients with moderate to severe periodontitis; subjects with periodontal healthy
Exclusion criteria: periodontal treatment or antibiotic therapy within the last 3 months; presence of any systemic disease (e.g.,diabetes mellitus, asthma); xerostomia or any other disease of the salivary glands; less than 20 teeth remaining; intake of any drug known to alter salivary rate levels (e.g., for sleeping disorders) or to be immunosuppressive; usage of partial or total prosthesis; pregnancy; lactation; acute infection; immunodeficiency; history of radio- or chemotherapy; and any conditions necessitating antibiotic premedication for dental appointment
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Interleukin 18. Timepoint: At the time of sampling. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method Interleukin 18. Timepoint: Six weeks after sampling. Method of measurement: ELISA kit.;Bleeding on probing. Timepoint: At the time of sampling. Method of measurement: By periodontal probe.