Gene Polymorphisms in Tacrolimus Drug Interactions

Completed

• Conditions: Renal Transplantation
• Interventions: Other: genotyping

• Registration Number: NCT00620841
• Lead Sponsor: KU Leuven

Brief Summary

A retrospective analysis of the influence of gene polymorphisms on drug interactions between calcineurin-inhibitors and concomitant drugs in renal transplant patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-05
• Status Verified: 2008-01
• Primary Completion: 2008-01
• Study Completion: 2008-01
• Study First Submitted: 2008-02-13
• Study First Submitted QC: 2008-02-21
• Last Update Submitted: 2008-02-21
• Study First Posted: 2008-02-22
• Last Update Posted: 2008-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Treatment with calcineurin-inhibitor
• Renal transplantation

Exclusion Criteria

• Drug, alcohol addiction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
A	genotyping	Patients treated with tacrolimus and experiencing a drug interaction

Primary Outcome Measures

Name	Time	Method
Tacrolimus exposure parameters	weeks

Secondary Outcome Measures

Name	Time	Method
Tacrolimus daily dosing	weeks

Trial Locations

Locations (1)

University Hospitals Leuven; 🇧🇪 Leuven, Brabant, Belgium