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临床试验/NCT00468572
NCT00468572已完成不适用

Affectionate Communication as a Mechanism for Responding to Acute Stress

Arizona State University2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2007年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
120
试验地点
2
主要终点
Cortisol levels

研究概览

简要总结

This study will examine the effects of tending to significant social relationships on managing and reducing stress.

详细描述

Stress is a large part of daily modern life; however, it can cause a number of long-term problems for mental and physical health. Recent research has confirmed that there are definite mental and physical health benefits of maintaining significant positive social bonds. Many of these benefits appear to be associated with the ability to regulate stress that is caused by environmental challenges. Drawing on close relationships and expressing affection may help people to recover from stress more effectively. This study will evaluate the tend-and-befriend theory, which suggests that engaging in behaviors aimed at maintaining and strengthening significant social bonds can act as an adaptive response to acute stress.

All participants in this study will undergo a series of standard laboratory stressors designed to elevate cortisol levels. Cortisol, also known as the "stress hormone," is activated and secreted within the body in response to stress. Current research suggests that displaying signs of affection toward a loved one can lower cortisol levels, causing the body to relax and recover from a stressful situation more quickly. After lab tests have been completed, participants will be randomly assigned to an experimental or control group. Participants assigned to the experimental group will spend 20 minutes writing an affectionate letter to a loved one. Participants assigned to the control group will spend 20 minutes writing about meaningless topics. Levels of cortisol will be measured using saliva samples from each participant during the writing session. Levels of oxytocin, a hormone known to transmit signals within the brain and often associated with bonding and building trusting relationships, will be measured from blood samples taken during the writing session as well. Participants will also provide a self-report of their current stress level at the end of the study. Participation in this study will last approximately 2 hours. By examining associations between the communication of affection and responses to acute stress, this study may eventually lead to the development of new and better treatment options for people with constant acute stress.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • English-speaking
  • Weigh at least 110 pounds
  • Moderate to no anxiety about having blood drawn

排除标准

  • Hypertension or diabetes
  • Current or recent pregnancy
  • Colorblindness
  • History of cancer
  • Current use of alpha blockers, beta blockers, or steroids

结局指标

主要结局

Cortisol levels

时间窗: Measured at Hour 2

Oxytocin levels

时间窗: Measured at Hour 2

次要结局

  • Self-reported stress level(Measured at Hour 2)

研究者

申办方类型
Other

研究点 (2)

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