Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.

Completed

• Conditions: Methemoglobinemia

• Registration Number: NCT01766999
• Lead Sponsor: University Hospital Schleswig-Holstein

Brief Summary

Tumescent local anesthesia is a procedure which is frequently performed for plastic cosmetic surgical procedures such as liposuction. The subcutaneous adipose tissue is infiltrated with large volumes of a solution which also contain local anesthetics. However local anesthetics, can also lead to a marked production of methemoglobin. New generation pulse oximeters are able to measure SpMetHb non-invasivly.

The aim of this study is:

1. to investigate multi-wavelength pulse oximetry as a monitoring method for patients at increased risk for methemoglobinemia.

2. to illustrate MetHb concentrations over a course of 24 hours after a liposuction employing tumescent anesthesia has been carried out.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-08
• Primary Completion: 2009-05
• Study Completion: 2010-12
• Study First Submitted: 2013-01-04
• Study First Submitted QC: 2013-01-09
• Study First Posted: 2013-01-11
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-02
• Last Update Posted: 2020-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 133

Inclusion Criteria

• planned liposuction in tumescent local anesthesia

Exclusion Criteria

• hematologic disorders

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between hemoximetric and pulseoximetric measured methemoglobin	24 hours

Secondary Outcome Measures

Name	Time	Method
Time course of MetHb concentration following liposuction employing tumescent anesthesia.	24 hours