Ovarian stimulation with r-FSH for women with high early follicular FSH and IUI indication.
Recruiting
- Conditions
- Subfertile women with elevated early follicular FSH values
- Registration Number
- NL-OMON23707
- Lead Sponsor
- VU University Medical Center, Devision of Reproductive Medicine
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. Women with elevated early follicular FSH (Cycle day 2-4);
2. Women between 18 and 45 years;
3. Regular menstrual cycle between 25 and 35 days;
4. Indication for IUI treatment;
5. Normal hysterosalpingography;
6. Normal serum Ca-125;
7. Semen analyses: > 2 million progressive motile spermatozoa;
8. Ovulatory cycle.
Exclusion Criteria
1. Untreated other endocrinal pathology;
2. Abnormal vaginal blood loss of unknown origine;
3. Contra-indications for use of r-FSH or hCG;
4. Contra-indications for pregnancy;
5. Congenital uterus anomaly;
6. Endometriosis more than stage II (revised ASRM score).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Multifollicular growth (on day of hCG administration, measured with ultrasound).
- Secondary Outcome Measures
Name Time Method 1. Pregnancy rate;<br>2. FSH doses used;<br>3. Cancellation rate;<br>4. Side-effects of medication;<br>5. Treatment load.