probiotic on oral aphtus ulcers

Phase 2

Recruiting

Conditions: oral recurrent aphtus ulcer.
Stomatitis and related lesions

Registration Number: IRCT20110428006322N2

Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

patients with oral aphtus ulcers between 15 -80 years old.
patients with oral aphtus ulcers without any systemic medication during last 6 months.
patients with one to three oral aphtus ulcers in their mouths
Patients with oral lesions that do not have a day off at the beginning of the lesion (the lesion is on the first day of appearance)
Patients with oral lesions that do not have a history of rheumatologic disease, GI disease, renal disease, and iron deficiency anemia.

Exclusion Criteria

Patients with oral aphtus lesions that have had a lesion more than one day.
pregnant patients
Patients with diffuse oral lesions and more than 3 concurrent lesions
Patients who do not have the opportunity to travel for frequent or repeated examinations.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The size of the lesions in millimeters. Timepoint: determination at 1,3,5 and 7 days. Method of measurement: size determination by ruler.;Severity of burning and pain based on visual analogue score (VAS) (score between 0-10). Timepoint: determination at 1,3,5 and 7 days. Method of measurement: Evaluation by VAS method and numerical expression of pain and burning intensity.;Duration of recovery in terms of number of days. Timepoint: daily check for seven days. Method of measurement: Improvement of clinical symptoms, absence of oral lesions and complete relief of burning and pain.

Secondary Outcome Measures