Submandibular gland sparing plus parotid sparing versus parotid sparing alone using volumetric modulated arc therapy (VMAT) in head and neck squamous cell carcinomas - a single blind phase 3 randomized controlled trial

JIPMER0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1. Patients over 18 years of age
•2. Patients with ECOG performance status 0 - 2
•3. Patients of squamous cell carcinoma of the
•head and neck planned for radical radiation with or without concurrent chemotherapy treated with volumetric modulated arc radiotherapy

•1. Patients with previous history of radiotherapy to head and neck
•2. Patients with T1N0M0 carcinoma glottis
•3. Patients with carcinoma of the head and
•neck in whom the submandibular glands are enclosed completely in the clinical target volume.
•4. Tumour involvement of both the submandibular glands
•5. Preâ??existing salivary gland disease
•6. Previous or concurrent illness that would
•compromise completion of treatment or
•7. Patient receiving prophylactic amifostine or pilocarpine

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