Exploring the Influence of GLP-1 Medications on External Food Cue Reactivity and Resultant Food Choice and Intake
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- Mean food cue reactivity scores in the afternoon
研究概览
简要总结
The purpose of this randomized control trial is to compare how food cravings, food selection, and food consumption change in response to frequent food advertisements compared to non-food advertisements in adults taking GLP-1 (weight loss) medications. The primary question we aim to answer is: do GLP-1 medications reduce an individual's vulnerability to external triggers that drive food cravings and consumption?
Participants will:
- report daily food consumption for a total of 10 days,
- receive eight daily prompts to view food or non-food related advertisements, and respond to a short 9-question survey for 7 days,
- answer several questionnaires,
- and complete two in-person visits to complete a virtual reality food selection task.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (18+) with overweight or obesity (BMI >25 kg/m2)
- •On an injectable form of tirzepatide GLP-1 medication at a minimum dose of 7.5 mg, taking it as prescribed by their doctor
- •Not currently taking an incretin-based medication at baseline other than the GLP-1 medication
- •Fluent in English
排除标准
- •Do not have consistent access to a smart phone that can access the study software
- •Diagnosed with cognitive or physical disability or epilepsy
- •Adults taking a compound GLP-1
研究组 & 干预措施
Food advertisement group
Advertisements viewed daily by this group will be food and/or beverage products
干预措施: Food advertisements (Behavioral)
Tech advertisement group
Individuals in this group will only receive tech-related advertisements daily
干预措施: Tech advertisements (Behavioral)
结局指标
主要结局
Mean food cue reactivity scores in the afternoon
时间窗: 7-day period of all afternoon survey responses
Average scores of craving levels for each group following afternoon advertisement viewing sessions
Mean food cue reactivity scores in the morning
时间窗: 7-day period of all morning survey responses
Average scores of craving levels for each group following morning advertisement viewing sessions
Mean food cue reactivity scores in the evening
时间窗: 7-day period of all evening survey responses
Average scores of craving levels for each group following evening advertisement viewing sessions
Mean food cue reactivity scores overall
时间窗: 7-day period of all survey responses
Average scores of craving levels for each group over all viewing sessions
Energy density of consumed foods
时间窗: 7 days
The energy density profile of foods consumed each day
次要结局
- Change from baseline in energy density of foods selected in the virtual buffet(Baseline and 7 days)
- Changes in food noise since being on medication questionnaire(Baseline)
- Changes in reasons for purchasing foods questionnaire(Baseline)
- Individual Food Cue Responsiveness--Trait(Baseline)
- Change in brand familiarity, liking, and/or craving(Baseline and 7 days)
研究者
Travis Masterson
Assistant Professor and Director of the Health, Ingestive Behavior, and Technology Lab
Penn State University