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Clinical Trials/ISRCTN73232918
ISRCTN73232918
Completed
Not Applicable

Primary prevention of rheumatoid arthritis

Jan van Breemen Instituut (Netherlands)0 sites80 target enrollmentDecember 20, 2005
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ConditionsRheumatoid arthritisMusculoskeletal Diseases

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rheumatoid arthritis
Sponsor
Jan van Breemen Instituut (Netherlands)
Enrollment
80
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 20, 2005
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Jan van Breemen Instituut (Netherlands)

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 18 \- 70 years for RF\+, 18\+ for aCCP
  • •2\. Twice increased Immunoglobulin M (IgM)\-RF and/or aCCP with 4\+ weeks interval
  • •3\. Human Leukocyte Antigen (HLA)\-DR Shared Epitope (SE) positive

Exclusion Criteria

  • •Situations with possible false positive RF:
  • •1\. Auto\-immune diseases
  • •2\. Active infection with hepatitis C or Ebstein Barr virus
  • •3\. Recent chemotherapy
  • •4\. Co\-morbidity with decreased life expectancy
  • •5\. Corticosteroid use for another disease
  • •6\. Contra\-indications for corticosteroids: diabetes mellitus, osteoporosis
  • •7\. Pregnancy or lactation

Outcomes

Primary Outcomes

Not specified

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