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Does melatonin improve the organ donation process?

Phase 3
Completed
Conditions
The present work quantifies the oxidative stress and miRNAs occurring in controlled donation after circulatory death and donation after brain death, and assesses its modulation after melatonin administration.
Not Applicable
Registration Number
ISRCTN66157570
Lead Sponsor
Fundación Mutua Madrileña
Brief Summary

2022 Other publications in https://doi.org/10.3390/healthcare10050762 Using malondialdehyde (MDA) measurement to assess oxidative stress (added 20/04/2022)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
53
Inclusion Criteria

1. Potential donors after circulatory or brain death
2. Patient suitable for organ donation under Spain’s National Transplant Organization protocols
3. Age above 18 years

Exclusion Criteria

1. Potential donors with multiorgan failure
2. Age below 17 years
3. Exclusion criteria for organ donation following Spain’s National Transplant Organization protocols

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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