NCT01349452已完成不适用
Ganciclovir 0,15% Ophthalmic Gel in the Treatment of Adenovirus Keratoconjuntivitis
Federal University of São Paulo1 个研究点 分布在 1 个国家目标入组 33 人开始时间: 2009年8月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- improvement of symptoms of conjunctivitis (pain relief)
研究概览
简要总结
Ganciclovir ophthalmic gel delivers multiple advantages in the treatment and prophylaxis of herpetic keratitis and shows potential for effectiveness against other viral ocular infections. The majority of adenoviral conjunctivitis will resolve without damaging vision, however, the investigators have no way to determine which cases will progress to ocular complications such as corneal infiltrates and pseudomembranes. Our purpose is to evaluate the efficacy of the Ganciclovir gel 0.15% in preventing ocular complications after adenoviral conjunctivitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •onset of symptoms for five days or less
- •eighteen years old or more
- •not pregnant or breastfeeding
- •be able to understand and sign the consent term
排除标准
- •use of antibiotic or corticoid 30 days before
- •monocular vision
- •keratopathy or other ocular diseases
研究组 & 干预措施
Ganciclovir
Experimental
干预措施: Ganciclovir (Drug)
Artificial tear
Sham Comparator
干预措施: Artificial tear (Drug)
结局指标
主要结局
improvement of symptoms of conjunctivitis (pain relief)
时间窗: 6 days
次要结局
未报告次要终点
研究者
研究点 (1)
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