Manitoba Inflammatory Bowel Disease Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 388
- 主要终点
- Genetic Associations
研究概览
简要总结
The Manitoba Inflammatory Bowel Disease (IBD) Cohort Study participants were drawn from a population-based research registry.
The cohort consisted of 388 adult enrollees with recent IBD onset who completed the baseline survey and interview in 2002 to 2003. Participants were followed every 6 months with surveys and annually with interviews. Diagnosis and disease type were verified by chart review.
详细描述
The Manitoba Inflammatory Bowel Disease (IBD) Cohort Study, initiated in 2002, is study of adults with IBD who have been tracked prospectively through annual clinical interviews and semiannual surveys. The participants were drawn from a validated population-based research registry, which identified and recruited individuals using an administrative definition of IBD from the comprehensive health data base of Manitoba Health, the single insurer that provides health care to all residents in the province.
The cohort consisted of 388 adult enrollees with recent IBD onset who completed the baseline survey and interview in 2002 to 2003. Participants were followed every 6 months with surveys and annually with interviews. Diagnosis and disease type were verified by chart review. It has been demonstrated that the Cohort is representative of the provincial IBD population as a whole, with comparable age distribution, sex distribution, disease duration, and rural/urban residence.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed within the previous 7 years with Inflammatory Bowel Disease
排除标准
- 未提供
结局指标
主要结局
Genetic Associations
时间窗: 2010 to 2016
Single Nucleotide Variations (SNPs) in gene encoding for membrane transporter proteins were investigated for associations with both IBDs. Target genes included SLC23A1, SLC22A4, SLC22A5, SLC22A23, SLC2A14, SLC2A2 but analyses are not limited to these.
次要结局
- Psychological Functioning 1(2010-2014)
- Self Efficacy(2010-2014)
- Disability(2010-2014)
- Health and Quality of Life 1(2010-2014)
- Disease Activity 1(2010-2014)
- Disease Activity 2(2010-2014)
- Disease Activity 3(2010-2014)
- Psychological Functioning 2(2010-2014)
- Psychological Functioning 3(2010-2014)
- Psychological Functioning 4(2010-2014)
- Health and Quality of Life 2(2010-2014)