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A single-centre study to check the visual performance and reduction in farsightedness in children with use of DIMSHYP spectacle lenses

Not Applicable
Conditions
Health Condition 1: H533- Other and unspecified disorders ofbinocular vision
Registration Number
CTRI/2024/08/072260
Lead Sponsor
Dr. Agarwal’s Eye Hospital Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Subjects’ age at time of parent (or guardian) consent and subject assent: 6 -9 years old.

2.Subjects with cycloplegic autorefraction SER between +2.00 D and +6.50 D.

3.Subjects with cycloplegic autorefraction astigmatism of 1.50 D or less.

4.Subjects with cycloplegic autorefraction anisometropia of 1.50 D or less.

5.Subjects with monocular best-corrected distance visual acuity (BCDVA) under cycloplegic equal to or better than logMAR 0.08 (better than 20/25).

6.Subjects in which baseline 3D macula optical coherence tomography (OCT) volume scan can clearly measure sub-foveal choroidal thickness.

7.Subjects and parents (or LAR) are able and willing to provide oral/verbal assent and consent, respectively.

8.Subjects and parents (or LAR) assure to attend required study visits and adhere to participant requirements.

9.The parent (or LAR) understands and accepts random allocation of grouping, and the subject and parent (or LAR) will not know the allocated group.

10.Subjects are willing to wear the study spectacle lens for a minimum of 12 hours per day for the duration of the study

Exclusion Criteria

1.Subjects with an allergy to fluorescein, benoxinate, proparacaine, tropicamide or cyclopentolate eye drops.

2.Subjects with any ocular and systemic abnormalities that might be expected to affect visual functions or refractive development.

3.Subjects with prior treatment of hyperopic control six months prior to the screening.

4.Subjects with clinically significant strabismus orbinocular vision abnormalities

5.Subjects with amblyopia or history of amblyopia.

6.Subjects with previous intraocular surgery.

7.Subjects with participation in a clinical trial within 30 days before the study entry into this study.

8.Subjects with presence of any emotional, physiologic or anatomical condition which may preclude participation in this study or provide an inappropriate landscape for the intended study treatment, based on the clinical judgment of the investigator.

9.Subjects with any medical treatment or medication which might influence the vision or interfere with study assessments.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate the effect of the DIMSHYP spectacle lens on visual performance and in refractive correction in non-diseased, non-amblyopic hyperopic children over a period of up to 24 months.Timepoint: Baseline and 24 months
Secondary Outcome Measures
NameTimeMethod
To evaluate the reduction of hyperopia with DIMSHYP spectacle lens in non-diseased, non-amblyopic hyperopic children over a period of up to 24 months.Timepoint: Baseline and 24 months
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