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Clinical Trials/NCT04484896
NCT04484896UnknownNot Applicable

Effects of Message Framing on Recruiting Rh-D Negative Blood Donors in an Emergency Situation

Guangzhou Blood Center1 site in 1 country1,082 target enrollmentStarted: July 22, 2020Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Sponsor
Enrollment
1,082
Locations
1
Primary Endpoint
Re-donation rate

Study Overview

Brief Summary

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 22, 2020 blood stockpile of O-negative and A-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and A-negative blood donors whose last donation dates were between January 1, 2018 and December 31, 2019 were identified and randomly assigned to four groups. Three different recruitment text messages were send three groups. We observed the re-donation rates among four groups within one week.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Other
Masking
Single (Participant)

Masking Description

Participant did not know the difference between the three message.

Eligibility Criteria

Ages
18 Years to 60 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •- O and A Rh- negative blood donors Last donations were between January 1, 2018 and December 31, 2019

Exclusion Criteria

  • •- With an obviously invalid phone number Serological results of the last donation were positive

Arms & Interventions

Control group

No Intervention

Donors in this group were not received SMS reminders.

Gain-frame Message

Experimental

Short messaging service (SMS) message: Dear group O/A Rh-D negative blood donor:

Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to save lives. Thank you for your support.

Please bring your identification (ID) card and show this message to our staff. Thank you.

Intervention: Gain-framed SMS message (Other)

Loss-frame Message

Experimental

SMS message: Dear group O/A Rh-D negative blood donor:

Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to prevent the loss of life. Thank you for your support.

Please bring your ID card and show this message to our staff. Thank you.

Intervention: Loss-framed SMS message (Other)

Information Message

Experimental

SMS message: Dear group O/A Rh-D negative blood donor:

Hello! The inventory of group O/A Rh-D negative blood product is low at present, if you can, please consider donating blood again. Thank you for your support.

Please bring your ID card and show this message to our staff. Thank you.

Intervention: Information SMS message (Other)

Outcomes

Primary Outcomes

Re-donation rate

Time Frame: 7 days

Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group divided by donors who re-donated within 7 days.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Guangzhou Blood Center
Sponsor Class
Other Gov
Responsible Party
Sponsor

Study Sites (1)

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