Local Injection of PRP During Repair of Disrupted Surgical Wounds

Not Applicable

Completed

• Conditions: Role of Platelet Rich Plasma in Wound Healing
• Interventions: Procedure: Platelet rich plasma infiltration in the wound edges; Procedure: Closure of wound without platelet rich plasma infiltration

• Registration Number: NCT03781882
• Lead Sponsor: Tanta University

Brief Summary

Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges

Detailed Description

The patients with disrupted surgical wounds will be cleansed, debrided and closed with infiltration of platelet rich plasma in one group and the other group will be closed without infiltration of Platelet rich plasma

Study Timeline

• Study First Submitted: 2018-12-18
• Study First Submitted QC: 2018-12-18
• Study First Posted: 2018-12-20
• Study Start: 2019-01-01
• Primary Completion: 2020-03-31
• Study Completion: 2020-03-31
• Status Verified: 2020-05
• Last Update Submitted: 2020-05-12
• Last Update Posted: 2020-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 220

Inclusion Criteria

• Disrupted surgical wounds after cesarean sections and other gynecological operations
• Body mass index 18-25
• Hemoglobin > 10.5gm/dl
• Albumin >3.5gm/dl

Exclusion Criteria

• Medical disorders asDiabetes mellitus (DM), Liver disease or systemic lupus erythymatosus (SLE)
• Patient on corticosteriod therapy
• Thrombocytopenia
• Coagulation disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention group	Platelet rich plasma infiltration in the wound edges	All patients in this group will be manged as usual with infiltration of platelet rich plasma in thee wound edges during closure of the wounds
Control group	Closure of wound without platelet rich plasma infiltration	All patients in this group will be managed by repair of wounds without infiltration of platelet rich plasma

Primary Outcome Measures

Name	Time	Method
Complete wound healing	30 days	time needed for complete wound closure
Duration of hospital stay	30 days	Time during which patient is admitted

Secondary Outcome Measures

Name	Time	Method
Failure of complete wound healing	30 days	No complete closure
Need fo tertiary suture	30 days	need to re-operate the case again

Trial Locations

Locations (1)

Ayman Shehata Dawood; 🇪🇬 Tanta, Egypt