To see the effect of adding clonidine with bupivacaine in scalp block for craniotomy patients
Phase 2
- Conditions
- Health Condition 1: G938- Other specified disorders of brain
- Registration Number
- CTRI/2024/02/062718
- Lead Sponsor
- Mahalakshmi S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 to 3
patients posted for elective craniotomy
Exclusion Criteria
1. Patient refusal
2. Emergency cases
3. Patients with uncontrolled hypertension
4. patients with preoperative bradycardia
5. patients with ischemic heart disease or cardiac arrhythmias
6. patients with severe pulmonary or hepatic or renal disease
7. drug allergy to local anesthetic used or clonidine
8. patients on alpha blockers preoperatively
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in mean arterial pressure in the intra operative periodTimepoint: Pulse rate systolic blood pressure diastolic blood pressure and mean arterial pressure will be recorded <br/ ><br>At baseline <br/ ><br>1, 3, 5 and 10 minutes after scalp block <br/ ><br>0, 2, 4, 6, 8, 10, 15, 20, 25, 30, 35 minutes after pin insertion
- Secondary Outcome Measures
Name Time Method 1. Post operative time duration for rescue analgesic <br/ ><br>2. Change in heart rate systolic blood pressure diastolic blood pressure and mean arterial pressure and pain score.Timepoint: Thirty minutes, first hour, second hour, fourth hour, eight hour, sixteenth hour and twenty fourth hour in post operative period.