Higher Protein Diet and Exercise for Optimal Weight Loss in Elderly Women
Phase 1
Completed
- Conditions
- Bone and Body CompositionObesityMetabolic SyndromePhysical FunctionQuality of Life
- Registration Number
- NCT00912210
- Lead Sponsor
- University of Illinois at Urbana-Champaign
- Brief Summary
The broad aim is to determine efficacy of a weight loss diet higher in protein and lower in carbohydrate combined with low intensity exercise to favorably impact body composition, bone health, physical function, metabolic disease and quality of life compared to a conventional higher carbohydrate diet in overweight women over age 60.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 31
Inclusion Criteria
- Body mass index > 28 kg/m²
- Clearance of primary physician to participate in diet and mild exercise
Exclusion Criteria
- Medical condition contraindicating prescribed diet and exercise regimen
- Type 2 Diabetes Mellitus
- Physically active lifestyle (>30 min moderate physical activity 2+ times weekly)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Bone and body composition: Weight, percent fat, muscle and fat distribution in the thigh and abdomen and bone density and structural quality assessed by DXA and structural MRI Baseline and post 6 months weight loss
- Secondary Outcome Measures
Name Time Method Quality of life Baseline and post 6 months weight loss Metabolic syndrome: insulin resistance, blood pressure, blood lipids, waist circumference Baseline and post 6 months weight loss Acid-base balance Baseline and post 1 and 6 months weight loss Physical function: balance, gait, strength and activities of daily living Baseline and post 6 months weight loss
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link higher protein intake to improved bone health in postmenopausal women with obesity?
How does a higher protein diet compare to standard low-fat diets in managing metabolic syndrome among elderly populations?
Which biomarkers predict response to low-intensity exercise combined with high-protein diets in sarcopenic obesity patients?
What adverse events are associated with high-protein weight loss regimens in geriatric individuals with metabolic disease?
Are there synergistic effects between resistance training and ketogenic diets for body composition changes in post-60 women?
Trial Locations
- Locations (1)
University of Illinois at Urbana-Champaign
🇺🇸Urbana, Illinois, United States
University of Illinois at Urbana-Champaign🇺🇸Urbana, Illinois, United States